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- Your Guide to Better Skin Exams (Pt. 2)
Your Guide to Better Skin Exams (Pt. 2)
Your Weekly Prompt to the Science of Skin and Success.

Welcome back, DERM Community!
Last week, we began our journey into one of the most foundational skills in dermatology: mastering the physical exam. It’s not just about examining the skin—it’s about noticing the details, like primary lesions, that guide you toward a precise diagnosis.
Now, we’re excited to bring you the second chapter of our two-part series on the physical exam and dermatologic diagnosis. This time, we’ll focus on secondary lesions—those crucial changes that reflect how a skin condition evolves. These are the key pieces that help you complete the diagnostic puzzle, offering a deeper understanding of what’s happening with your patient.
At Derm for Primary Care, our goal is to support you every step of the way. So, dive into this week’s issue, absorb the practical tips, and keep honing your diagnostic skills.
(Don’t forget to download our FREE cheat guide on better skin exams at the end of this issue!) 😉
Featured on This Week’s Chapter:
🚀 Learning Opportunities: Understanding Secondary Lesions

Understanding Secondary Lesions: What They Tell Us About the Skin’s Response
While primary lesions are often the first step in recognizing dermatologic conditions, secondary lesions offer valuable insights into the body’s response. Secondary lesions can help differentiate between ongoing, healing, or resolved skin conditions and guide further treatment and management strategies.
A comprehensive dermatologic exam involves identifying both primary and secondary lesions. Secondary lesions typically develop from primary lesions or as a result of external factors, and they often signal the stage or severity of a skin condition.
Here’s what you need to know to identify and interpret secondary lesions in clinical practice effectively.
You’ll learn about:
The Characteristics of Secondary Lesions
Common Types of Secondary Lesions
Key Factors that Influence Lesion Appearance
The Characteristics of Secondary Lesions
Secondary lesions may appear differently depending on the skin’s healing process, environmental influences, or the underlying condition. Understanding these lesions is essential for tracking disease progression and evaluating treatment outcomes.
Scale: Shedding of superficial epidermal cells, often seen as flaking or peeling of the skin.
Crust: Dried serum, blood, or exudate on the skin’s surface, often a result of skin inflammation.
Excoriation: Scratches caused by constant scratching, frequently associated with itching disorders like eczema and scabies.
Erosion: The loss of epidermal surface, often following a blister rupture, leaving an area of raw skin.
Pigmentation Change: Post-inflammatory changes in skin color, which can appear lighter or darker depending on the individual’s skin type.
Common Types of Secondary Lesions
Lesion Type | Description | Examples |
Scarring | Resulting from deeper dermal damage, scarring can occur due to wound healing and may lead to permanent skin changes. | Healing after trauma, surgical incisions, or inflammatory acne. |
Fissures | Deep cracks or breaks in the skin, often seen in conditions with extreme dryness. | Hand eczema, athlete's foot, or severely dry skin. |
Atrophy | Thinning of the skin, often following prolonged use of topical steroids or conditions like lupus. | Steroid-induced skin thinning, discoid lupus erythematosus. |
Lichenification | Thickened skin with accentuated lines, often a result of chronic scratching or rubbing. | Chronic eczema, prurigo nodularis. |
Burrow | A serpentine tunnel under the skin, caused by parasitic infestations like scabies. | Scabies infestation. |
Erythema | Redness of the skin, indicating inflammation, often seen with allergic reactions or infections. | Allergic reactions, cellulitis, or dermatitis. |
Key Factors that Influence Lesion Appearance
Several factors can affect how a secondary lesion presents, including the time course of the disease, the patient's skin type, and their immune status. Understanding these variables is essential for accurate diagnosis.
Time Course: The appearance of a lesion can change as a disease progresses. In some cases, early-stage lesions may be difficult to identify, requiring follow-up exams as the disease develops.
Skin of Color: Pigmentation changes may be more noticeable or pronounced in darker skin types, requiring a more nuanced approach to evaluation.
Immune Status: Patients with compromised immune systems may present with altered or atypical exam findings, complicating diagnosis.
What Every Clinician Should Remember
Secondary lesions provide critical information about disease progression and treatment effectiveness.
Regular follow-up and serial examinations help track lesion evolution and refine diagnosis.
Factors such as skin color and immune status can significantly influence lesion appearance and clinical interpretation.
Identifying and understanding secondary lesions allows for more accurate and timely diagnoses, enhancing patient care.
Better Skin Exams: The Cheat Guide
Download our FREE cheat guide on better skin exams (and keep it on your phone or in your notes for easy reference!)
For a more in-depth resource, explore our CE course, "Physical Exam & Dermatologic Diagnosis.”
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Ready to dive deeper into dermatologic diagnosis? Our CE course, Physical Exam & Dermatologic Diagnosis, explores secondary lesions in detail, helping you improve your diagnostic skills and apply them to a range of common skin conditions. Learn how to spot secondary lesions, track disease progression, and optimize patient care with a systematic approach.
This course will guide you through the complexities of identifying both primary and secondary lesions, enhancing your ability to diagnose skin conditions effectively.
📚 Why Choose Us for Your Continuing Education?
For all healthcare practitioners:
↳ Flexible learning: Fit your studies around your schedule.
↳ Real-world impact: Elevate your care with the latest in dermatology.
Earn your CE credits with one of the greatest educational platforms across the U.S.
👋🏻 Until next time!
Thanks for tuning in to Beneath the Surface.
We’re grateful to have you on this journey with us, where expert insights meet real-world application in dermatology.
Let’s continue to learn, grow, and innovate together to advance the field and provide the best care for our patients.
Stay curious, stay connected, stay DERM!
— The Derm for Primary Care Team
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