Impetigo Demystified: Spotting the Signs and Preventing the Spread

Your Weekly Prompt to the Science of Skin and Success.

Welcome back, DERM Community!

Last week, we pulled back the curtain on herpes, one of the most stigmatized yet misunderstood conditions in dermatology. Missed it? Don’t worry: you can still catch up on the red flags and myths that matter.

This week in Beneath the Surface, we’re focusing on Impetigo, a disease that can be overwhelming and scary. In our course we dive deep into real clinical cases, but today, let’s start with the essentials.

What is Impetigo?

It is a deceptively simple infection that continues to challenge clinicians, especially when it mimics other dermatologic conditions or goes unrecognized in adults.

Whether it’s classic honey-colored crusts or subtle bullae, impetigo is more than “just a kid’s rash” and it deserves a closer look.

How It Spreads

Impetigo is highly contagious and spreads through:

  • Direct skin contact with infected lesions

  • Fomites like towels, bedding, or toys

  • Auto-inoculation from scratching

It thrives in settings like schools, daycares, and athletic teams, especially with poor hygiene or skin barrier disruptions (such as eczema, insect bites, minor trauma).

Why Recognizing It Matters

Impetigo isn’t just a nuisance, it can lead to complications such as:

  • Post-streptococcal glomerulonephritis

  • Cellulitis or deeper skin infections

  • MRSA transmission in community settings

And it’s often misdiagnosed as:

  • HSV (especially bullous impetigo)

  • Contact dermatitis

  • Tinea infections

  • Atopic eczema flare-ups

Early diagnosis is key to:

  • Starting topical or systemic antibiotics promptly

  • Preventing outbreaks in household or school settings

  • Avoiding unnecessary treatments or workups

Keep an eye out for rapidly spreading lesions, crusting, and mild pruritus or discomfort, especially when they appear in clusters or after minor trauma. Swabbing for culture may help when lesions are atypical or treatment fails.

Too much information?

Here’s a FREE guide for you to check it out later or share with your patients:

FREE Guide on Impetigo.pdf5.60 MB • PDF File

👋🏻 See you next Thursday, DERM community!

Impetigo may seem straightforward, but its clinical mimics, public health implications, and potential complications make it a condition worth mastering.

By staying sharp in your recognition, treatment, and prevention strategies, you’re not just curing skin, you’re curbing spread and protecting communities.

Seen an impetigo case that threw you off? A resistant bug that challenged your go-to treatment plan?

Hit reply, we want to hear your stories and may feature them in an upcoming issue.

Stay sharp, stay curious, and help patients feel seen, not judged.

— The Derm for Primary Care Team

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